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Detailed description page of ParaPep

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1262 details
Primary information
ParaPep ID1262
PMID8450035
YEAR1993
SEQUENCEL-HPhe
LENGTH2
NAMEFluoromethyl ketone proteinase inhibitor
C-ter ModificationCH2F
N-ter ModificationMu=Morpholine urea
Linear/CyclicLinear
StereochemistryL
Chemical ModificationHPhe=Homophenylalanine
DiseaseMalaria
AssayMicroscopy (Giemsa staining)
Parasite TypePlasmodium falciparum Itg2
In-vivo/vitroIn vitro
ActivityIC50=0.42 nM
HemolysisNot reported
NatureCysteine proteinase inhibitor
Secondary information
STRUCTURE
3-D Structure
DSSP statesNA
SMILES[C@H](CCC1CCCCC1)(C(=O)OF)N[C@@H]([C@H](CC(C)C)NN[C@@H](NN1CCOCC1)O)O
External Links
PDB exactPDB partialUP exactUP exactTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA