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Detailed description page of ParaPep

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1120 details
Primary information
ParaPep ID1120
PMID19752273
YEAR2009
SEQUENCELL-Nle
LENGTH3
NAMEALLN
C-ter ModificationFree
N-ter ModificationAcetylation
Linear/CyclicLinear
StereochemistryL
Chemical ModificationNle=Norleucinal
DiseaseMalaria
Assay[3H] Hypoxanthine incorporation assay
Parasite TypePlasmodium falciparum 3D7 parasite line
In-vivo/vitroIn vitro
ActivityIC50=72.4±7.8μM
HemolysisNot reported
NatureProteasome inhibitor
Secondary information
STRUCTURE
3-D Structure
DSSP statesNA
SMILESN([C@H](C(=O)N[C@@H](CCCC)[C@H](O)O)CC(C)C)C(=O)[C@H](CC(C)C)NCOC
External Links
PDB exactPDB partialUP exactUP exactTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA