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Receptor

Search Result - 1

HMRbase accession number	22992
Swiss-prot Accession number	O75787 (Sequence in FASTA format)
Description	Renin receptor;Alternative Name: Renin/prorenin receptor;Alternative Name: ATPase H(+)-transporting lysosomal accessory protein 2;Alternative Name: ATPase H(+)-transporting lysosomal-interacting protein 2;Alternative Name: Vacuolar ATP synthase membrane sector-associated protein M8-9;Short=V-ATPase M8.9 subunit;Alternative Name: ATP6M8-9;Alternative Name: N14F;Alternative Name: ER-localized type I transmembrane adaptor;Alternative Name: Embryonic liver differentiation factor 10;Precursor
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; Single-pass type I membrane protein (Potential)
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncitiotrophoblast cells in the mature fetal placenta.
Post translational modification	Phosphorylated.
Function	Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS).
Protein Length	350 Amino acids
Molecular weight	39008
Domain Name	Renin_r
References	1  PubMed abstract 12045255 2  PubMed abstract 10931946 3  PubMed abstract 15489334 4  PubMed abstract 9556572 5  PubMed abstract 15746149
Hormone	P00797   Detail in HMRbase    Q6FI38   Detail in HMRbase
Gene ID	10159
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 2

HMRbase accession number	22993
Swiss-prot Accession number	Q9CYN9 (Sequence in FASTA format)
Description	Renin receptor;Alternative Name: Renin/prorenin receptor;Alternative Name: ATPase H(+)-transporting lysosomal accessory protein 2;Alternative Name: ATPase H(+)-transporting lysosomal-interacting protein 2;Precursor
Source organism	Mus musculus (Mouse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular location	Membrane; Single-pass type I membrane protein (Potential)
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	Phosphorylated (By similarity).
Function	Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) (By similarity).
Protein Length	350 Amino acids
Molecular weight	39092
Domain Name	Renin_r
References	1  PubMed abstract 16141072 2  PubMed abstract 15489334
Hormone	P06281   Detail in HMRbase    P00796   Detail in HMRbase    Q9JM79   Detail in HMRbase
Gene ID	70495
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 3

HMRbase accession number	22994
Swiss-prot Accession number	Q5R563 (Sequence in FASTA format)
Description	Renin receptor;Alternative Name: Renin/prorenin receptor;Alternative Name: ATPase H(+)-transporting lysosomal accessory protein 2;Alternative Name: ATPase H(+)-transporting lysosomal-interacting protein 2;Precursor
Source organism	Pongo abelii (Sumatran orangutan)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pongo.
Subcellular location	Membrane; Single-pass type I membrane protein (Potential)
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	Phosphorylated (By similarity).
Function	Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) (By similarity).
Protein Length	350 Amino acids
Molecular weight	39008
Domain Name	Renin_r
References	----
Hormone	N/A
Gene ID	100173844
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 4

HMRbase accession number	22995
Swiss-prot Accession number	Q6AXS4 (Sequence in FASTA format)
Description	Renin receptor;Alternative Name: Renin/prorenin receptor;Alternative Name: ATPase, H(+)-transporting, lysosomal accessory protein 2;Alternative Name: ATPase, H(+)-transporting, lysosomal-interacting protein 2;Precursor
Source organism	Rattus norvegicus (Rat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular location	Membrane; Single-pass type I membrane protein (Potential)
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	Phosphorylated (By similarity).
Function	Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) (By similarity).
Protein Length	350 Amino acids
Molecular weight	39082
Domain Name	Renin_r
References	1  PubMed abstract 15489960 2  PubMed abstract 15489334
Hormone	P08424   Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 5

HMRbase accession number	22996
Swiss-prot Accession number	B5X2F3 (Sequence in FASTA format)
Description	Renin receptor
Source organism	Salmo salar (Atlantic salmon)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Salmo.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	362 Amino acids
Molecular weight	40420
Domain Name	Renin_r
References	----
Hormone	N/A
Gene ID	100195062
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 6

HMRbase accession number	22997
Swiss-prot Accession number	Q5M8F1 (Sequence in FASTA format)
Description	Hypothetical LOC496778 (Renin receptor) (Renin/prorenin receptor) (ATPase, H+ transporting, lysosomal accessory protein 2) (ATPase, H+ transporting, lysosomal interacting protein 2)
Source organism	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Silurana.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	348 Amino acids
Molecular weight	38931
Domain Name	Renin_r
References	----
Hormone	N/A
Gene ID	496778
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated