A database of hormones and their receptors |
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HMRbase accession number | 21435 |
Swiss-prot Accession number | Q9GLW0 (Sequence in FASTA format) |
Description | Progesterone receptor;PR;Alternative Name: Nuclear receptor subfamily 3 group C member 3 |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Nucleus. Note=Diverse nuclear localization patterns of PR observed in tumorous mammary and uterine tissue, including strong nuclear or perinuclear localization, heterogeneous expression or complete lack of expression, depending on tumor type and stage |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | Expressed in mammary gland and uterus. |
Post translational modification | N/A |
Function | The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. |
Protein Length | 939 Amino acids |
Molecular weight | 98418 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 11282275 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | 403621 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21436 |
Swiss-prot Accession number | P07812 (Sequence in FASTA format) |
Description | Progesterone receptor;PR;Alternative Name: Nuclear receptor subfamily 3 group C member 3 |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Nucleus |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | Oviduct and bursa of Fabricius. |
Post translational modification | Phosphorylation of Ser-529 is sharply incrased upon progesterone treatment, whereas phosphorylation of Ser-210 and Ser-259 is modestly induced by progesterone. |
Function | The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. |
Protein Length | 786 Amino acids |
Molecular weight | 85744 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 3443098 2 PubMed abstract 3153474 3 PubMed abstract 2303488 4 PubMed abstract 2426779 5 PubMed abstract 3453892 6 PubMed abstract 3653503 7 PubMed abstract 2398063 8 PubMed abstract 2426697 9 PubMed abstract 2760059 10 PubMed abstract 7877616 11 PubMed abstract 8662804 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | 396198 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21437 |
Swiss-prot Accession number | P06401 (Sequence in FASTA format) |
Description | Progesterone receptor;PR;Alternative Name: Nuclear receptor subfamily 3 group C member 3 |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Nucleus |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. |
Protein Length | 933 Amino acids |
Molecular weight | 98981 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 2328727 2 PubMed abstract 3551956 3 PubMed abstract 11110801 4 PubMed abstract 12917342 5 PubMed abstract 16478993 6 PubMed abstract 17347654 7 PubMed abstract 18088087 8 PubMed abstract 9620806 9 PubMed abstract 15937332 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | 5241 |
PDB ID | 1A28 1E3K 1SQN 1SR7 1ZUC 2C7A 2OVH 2OVM |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21439 |
Swiss-prot Accession number | Q00175 (Sequence in FASTA format) |
Description | Progesterone receptor;PR;Alternative Name: Nuclear receptor subfamily 3 group C member 3 |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Nucleus |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. |
Protein Length | 923 Amino acids |
Molecular weight | 99074 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 2069958 2 PubMed abstract 7802637 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21440 |
Swiss-prot Accession number | P06186 (Sequence in FASTA format) |
Description | Progesterone receptor;PR;Alternative Name: Nuclear receptor subfamily 3 group C member 3 |
Source organism | Oryctolagus cuniculus (Rabbit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular location | Nucleus |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. |
Protein Length | 930 Amino acids |
Molecular weight | 98667 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 3538016 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | 100009094 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21441 |
Swiss-prot Accession number | Q8AYI2 (Sequence in FASTA format) |
Description | Progesterone receptor;PR;Alternative Name: dyPR;Alternative Name: Nuclear receptor subfamily 3 group C member 3 |
Source organism | Rana dybowskii (Dybovsky's frog) (Korean brown frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Rana. |
Subcellular location | Nucleus. Note=Predominantly nuclear |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | Expressed in all tissues examined: highly expressed in testis and brain. Also expressed in heart, lung, liver, kidney, stomach and small intestine. |
Post translational modification | N/A |
Function | The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. |
Protein Length | 711 Amino acids |
Molecular weight | 80126 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 14644654 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21442 |
Swiss-prot Accession number | Q63449 (Sequence in FASTA format) |
Description | Progesterone receptor;PR;Alternative Name: Nuclear receptor subfamily 3 group C member 3 |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Nucleus |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. |
Protein Length | 923 Amino acids |
Molecular weight | 99408 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 8299566 2 PubMed abstract 1840636 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | 25154 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21443 |
Swiss-prot Accession number | Q28590 (Sequence in FASTA format) |
Description | Progesterone receptor;PR;Alternative Name: Nuclear receptor subfamily 3 group C member 3; Fragment |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Nucleus |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. |
Protein Length | 377 Amino acids |
Molecular weight | 42904 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22080 |
Swiss-prot Accession number | Q690N0 (Sequence in FASTA format) |
Description | Progesterone receptor; Fragment |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 482 Amino acids |
Molecular weight | 53591 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 15930184 |
Hormone | Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22201 |
Swiss-prot Accession number | Q6TZ08 (Sequence in FASTA format) |
Description | Progesterone receptor; Fragment |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 255 Amino acids |
Molecular weight | 28727 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22339 |
Swiss-prot Accession number | Q863K6 (Sequence in FASTA format) |
Description | Progesterone receptor; Fragment |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 383 Amino acids |
Molecular weight | 43590 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | ---- |
Hormone | Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22417 |
Swiss-prot Accession number | Q8BW69 (Sequence in FASTA format) |
Description | Putative uncharacterized protein; Fragment |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 698 Amino acids |
Molecular weight | 75476 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 |
Hormone | N/A |
Gene ID | 18667 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22490 |
Swiss-prot Accession number | Q8NG42 (Sequence in FASTA format) |
Description | Delta 6/2 progesterone receptor;Progesterone receptor, isoform CRA_a |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 803 Amino acids |
Molecular weight | 83662 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 12673676 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22491 |
Swiss-prot Accession number | Q8NG43 (Sequence in FASTA format) |
Description | Delta4+6/2 progesterone receptor |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 690 Amino acids |
Molecular weight | 71212 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 12673676 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22492 |
Swiss-prot Accession number | Q8NG44 (Sequence in FASTA format) |
Description | Delta 3+6/2 progesterone receptor;Progesterone receptor, isoform CRA_e |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 764 Amino acids |
Molecular weight | 79315 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 12673676 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22493 |
Swiss-prot Accession number | Q8NG45 (Sequence in FASTA format) |
Description | Progesterone receptor;Progesterone receptor, isoform CRA_f |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 695 Amino acids |
Molecular weight | 71728 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 12579263 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22521 |
Swiss-prot Accession number | Q8TDS3 (Sequence in FASTA format) |
Description | Delta 4 progesterone receptor;Progesterone receptor, isoform CRA_c |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 831 Amino acids |
Molecular weight | 87747 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 9598870 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22529 |
Swiss-prot Accession number | Q8UVY3 (Sequence in FASTA format) |
Description | Oviduct progesterone receptor; Fragment |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 703 Amino acids |
Molecular weight | 79047 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | ---- |
Hormone | Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22719 |
Swiss-prot Accession number | Q9DDU9 (Sequence in FASTA format) |
Description | Progesterone receptor (Pgr-A protein) |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 732 Amino acids |
Molecular weight | 82022 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 11114187 |
Hormone | Detail in HMRbase |
Gene ID | 373633 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22725 |
Swiss-prot Accession number | Q9DEV4 (Sequence in FASTA format) |
Description | Progesterone receptor PR |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 583 Amino acids |
Molecular weight | 66156 |
Domain Name | Hormone_recep Prog_receptor zf-C4 |
References | 1 PubMed abstract 11050156 |
Hormone | Detail in HMRbase |
Gene ID | 373629 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |