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Receptor

Search Result - 1

HMRbase accession number	20028
Swiss-prot Accession number	Q28616 (Sequence in FASTA format)
Description	Anti-Muellerian hormone type-2 receptor precursor (EC 2.7.11.30)(Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIStype II receptor) (MISRII) (MRII).
Source organism	Oryctolagus cuniculus (Rabbit)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus.
Subcellular location	Membrane; single-pass type I membrane protein (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the Ser/Thr protein kinase family. TGFB receptor subfamily. Contains 1 protein kinase domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
Protein Length	569 Amino acids
Molecular weight	61099
Domain Name	Pkinase  Pkinase_Tyr
References	1  PubMed abstract 7997230
Hormone	N/A
Gene ID	100009599
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 2

HMRbase accession number	21074
Swiss-prot Accession number	Q16671 (Sequence in FASTA format)
Description	Anti-Muellerian hormone type-2 receptor precursor (EC 2.7.11.30)(Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIStype II receptor) (MISRII) (MRII).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; single-pass type I membrane protein
Developmental Stage	N/A
Similarity	Belongs to the Ser/Thr protein kinase family. TGFB receptor subfamily. Contains 1 protein kinase domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
Protein Length	573 Amino acids
Molecular weight	62750
Domain Name	Pkinase  Pkinase_Tyr
References	1  PubMed abstract 7493017 2  PubMed abstract 7488027 3  PubMed abstract 10589763 4  PubMed abstract 15489334 5  PubMed abstract 8872466 6  PubMed abstract 11549681
Hormone	P03971   Detail in HMRbase
Gene ID	269
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 3

HMRbase accession number	21110
Swiss-prot Accession number	Q62893 (Sequence in FASTA format)
Description	Anti-Muellerian hormone type-2 receptor precursor (EC 2.7.11.30)(Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIStype II receptor) (MISRII) (MRII) (C14).
Source organism	Rattus norvegicus (Rat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular location	Membrane; single-pass type I membrane protein
Developmental Stage	Expressed in the mesenchymal cells surrounding the Muellerian duct at embryonic days 14, 15, and 16 and in tubular and follicular structures of the fetal gonads.
Similarity	Belongs to the Ser/Thr protein kinase family. TGFB receptor subfamily. Contains 1 protein kinase domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
Protein Length	557 Amino acids
Molecular weight	59749
Domain Name	Pkinase  Pkinase_Tyr
References	1  PubMed abstract 8536608 2  PubMed abstract 8119126 3  PubMed abstract 10570158
Hormone	P49000   Detail in HMRbase
Gene ID	29530
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 4

HMRbase accession number	21148
Swiss-prot Accession number	Q8K592 (Sequence in FASTA format)
Description	Anti-Muellerian hormone type-2 receptor precursor (EC 2.7.11.30)(Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIStype II receptor) (MISRII) (MRII).
Source organism	Mus musculus (Mouse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular location	Membrane; single-pass type I membrane protein (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the Ser/Thr protein kinase family. TGFB receptor subfamily. Contains 1 protein kinase domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
Protein Length	568 Amino acids
Molecular weight	61195
Domain Name	Pkinase  Pkinase_Tyr
References	1  PubMed abstract 9299437 2  PubMed abstract 15489334
Hormone	P27106   Detail in HMRbase
Gene ID	110542
PDB ID	N/A
Drugpedia	wiki
Comments