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Receptor

Search Result - 1

HMRbase accession number	20032
Swiss-prot Accession number	Q14246 (Sequence in FASTA format)
Description	EGF-like module-containing mucin-like hormone receptor-like 1precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 6 EGF-like domains. Contains 1 GPS domain.
Tissue Specificity	Wide expression; increased levels in peripheral blood mononuclear cells.
Post translational modification	N/A
Function	Could be involved in cell-cell interactions.
Protein Length	886 Amino acids
Molecular weight	97625
Domain Name	7tm_2  EGF_CA  GPS  EGF
References	1  PubMed abstract 7601460 2   Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 3  PubMed abstract 15489334
Hormone	N/A
Gene ID	2015
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 2

HMRbase accession number	20033
Swiss-prot Accession number	Q61549 (Sequence in FASTA format)
Description	EGF-like module-containing mucin-like hormone receptor-like 1precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor)(Cell surface glycoprotein F4/80).
Source organism	Mus musculus (Mouse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 7 EGF-like domains. Contains 1 GPS domain.
Tissue Specificity	In macrophages; but absent from those which are localized within T-cell areas of lymph nodes and spleen. Low level of expression on blood monocytes.
Post translational modification	N/A
Function	Could be involved in cell-cell interactions.
Protein Length	931 Amino acids
Molecular weight	102130
Domain Name	7tm_2  EGF_CA  GPS  EGF
References	1  PubMed abstract 8550607 2  PubMed abstract 9169125 3  PubMed abstract 15489334
Hormone	N/A
Gene ID	13733
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 3

HMRbase accession number	20035
Swiss-prot Accession number	Q2Q421 (Sequence in FASTA format)
Description	EGF-like module-containing mucin-like hormone receptor-like 2precursor (EGF-like module EMR2) (CD312 antigen).
Source organism	Canis familiaris (Dog)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 5 EGF-like domains. Contains 1 GPS domain.
Tissue Specificity	N/A
Post translational modification	Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit (By similarity).
Function	Receptor probably involved in cell attachment (By similarity).
Protein Length	830 Amino acids
Molecular weight	91452
Domain Name	7tm_2  EGF_CA  GPS  EGF
References	1   Kwakkenbos M.J., Matmati M., Pouwels W., Wang Y., Bontrop R.E.,Heidt P.J., Hoek R.M., Hamann J.; "A unique mode of concerted evolution of the EGF-TM7 receptor chimeraEMR2."; Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	610750
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated