A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21146 |
| Swiss-prot Accession number | Q8JZL2 (Sequence in FASTA format) |
| Description | Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCHR-1)(MCH-R1) (MCH1R) (MCH-1R) (MCHR) (G-protein coupled receptor 24)(Somatostatin receptor-like protein) (SLC-1). |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. |
| Protein Length | 423 Amino acids |
| Molecular weight | 46269 |
| Domain Name | 7tm_1 |
| References | 1 Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 16141072 3 Lakaye B., Adamantidis A., Coumans B., Zorzi W., Parmentier M.,Grisar T.; "Cloning of the mouse melanin-concentrating hormone receptor 1 geneand promoter characterization."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 11471062 5 Ehringer M.A., Thompson J., Conroy O., Xu Y., Yang F., Canniff J.,Beeson M., Gordon L., Bennett B., Johnson T.E., Sikela J.M.; Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases. |
| Hormone | P56942 Detail in HMRbase |
| Gene ID | 207911 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |