A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20410 |
| Swiss-prot Accession number | Q8BZI5 (Sequence in FASTA format) |
| Description | Adult male diencephalon cDNA, RIKEN full-length enriched library,clone:9330209K16 product:5-HYDROXYTRYPTAMINE 2C RECEPTOR, full insertsequence. |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Membrane (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
| Protein Length | 459 Amino acids |
| Molecular weight | 51915 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. |
| Hormone | N/A |
| Gene ID | 15560 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |