A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20408 |
| Swiss-prot Accession number | Q8BGS4 (Sequence in FASTA format) |
| Description | 10 days neonate cortex cDNA, RIKEN full-length enriched library,clone:A830017H24 product:5-HYDROXYTRYPTAMINE 1A RECEPTOR (5-HT-1A)(SEROTONIN RECEPTOR) (5- HT1A), full insert sequence (Adult malecorpora quadrigemina cDNA, RIKEN full-length enriched library,clone:B230339C01 product:5-hydroxytryptamine (serotonin) receptor 1A,full insert sequence) (Adult male hippocampus cDNA, RIKEN full-lengthenriched library, clone:C630007E24 product:5-HYDROXYTRYPTAMINE 1ARECEPTOR (5-HT-1A) (SEROTONIN RECEPTOR) (5- HT1A), full insertsequence) (Adult male hippocampus cDNA, RIKEN full-length enrichedlibrary, clone:C630001G15 product:5-HYDROXYTRYPTAMINE 1A RECEPTOR (5-HT-1A) (SEROTONIN RECEPTOR) (5- HT1A), full insert sequence). |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Membrane (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
| Protein Length | 421 Amino acids |
| Molecular weight | 46176 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 9 Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K.,Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S.,Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N.,Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D.,Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A.,Muramatsu M., Hayashizaki Y.; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. |
| Hormone | N/A |
| Gene ID | 15550 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |