A database of hormones and their receptors
Receptor

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HMRbase accession number20342
Swiss-prot Accession numberO70528 (Sequence in FASTA format)
Description5-hydroxytryptamine 4 receptor (5-HT-4) (Serotonin receptor 4) (5-HT4).
Source organismCavia porcellus (Guinea pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia.
Subcellular locationCell membrane; multi-pass membrane protein
Developmental StageN/A
Similarity Belongs to the G-protein coupled receptor 1 family.
Tissue SpecificityN/A
Post translational modification N/A
Function This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity).
Protein Length388 Amino acids
Molecular weight43726
Domain Name7tm_1  
References1   Van den Wyngaert I., Gommeren W., Jurzak M., Verhasselt P., Gordon R.,Leysen J., Luyten W., Bender E.; "Cloning and expression of 5-HT4 receptor species and splicevariants."; Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.
HormoneN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Hormone for this Receptor are either unknown or have not yet been curated