A database of hormones and their receptors
Home
Hormone
Receptor
Tools
Miscellaneous
Contact
Peptide Hormone

Search Result - 1

HMRbase accession number11337
Swiss-prot Accession numberP01308 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight11981
References1  PubMed abstract 6243748
2  PubMed abstract 6248962
3  PubMed abstract 503234
4  PubMed abstract 6927840
5  PubMed abstract 8358440
6   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
7  PubMed abstract 15489334
8   Fajardy I.I., Weill J.J., Stuckens C.C., Danze P.M.P.; "Description of a novel RFLP diallelic polymorphism (-127 BsgI C/G)within the 5' region of insulin gene."; Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
9  PubMed abstract 14426955
10  PubMed abstract 5101771
11  PubMed abstract 5560404
12  PubMed abstract 4443293
13  PubMed abstract 4803504
14  PubMed abstract 4698555
15  PubMed abstract 4698553
16  PubMed abstract 6312455
17  PubMed abstract 6424111
18  PubMed abstract 3470784
19  PubMed abstract 3537011
20  PubMed abstract 2196279
21  PubMed abstract 4019786
22  PubMed abstract 1601997
23  PubMed abstract 2271664
24  PubMed abstract 2036420
25  PubMed abstract 1646635
26  PubMed abstract 1433291
27  PubMed abstract 8421693
28  PubMed abstract 9235985
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorP06213    Detail in HMRbase   
Gene ID3630      
PDB ID1A7F   1AI0   1AIY   1B9E   1BEN   1EFE   1EV3   1EV6   1EVR   1FU2   1FUB   1G7A   1G7B   1GUJ   1HIQ   1HIS   1HIT   1HLS   1HTV   1HUI   1IOG   1IOH   1J73   1JCA   1JCO   1K3M   1KMF   1LKQ   1LPH   1MHI   1MHJ   1MSO   1OS3   1OS4   1QIY   1QIZ   1QJ0   1RWE   1SF1   1SJT   1SJU   1T0C   1T1K   1T1P   1T1Q   1TRZ   1TYL   1TYM   1UZ9   1VKT   1W8P      
Drugpediawiki
Comments