A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10943
Swiss-prot Accession numberP10000 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha (Alpha-MSH); Corticotropin-like intermediarypeptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH); Beta-endorphin; Met-enkephalin].
Source organismOncorhynchus keta (Chum salmon)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length226 Amino acids
Molecular weight24982
References1  PubMed abstract 3197404
2  PubMed abstract 6095185
3  PubMed abstract 6087806
4  PubMed abstract 7447938
5  PubMed abstract 475783
6  PubMed abstract 3197404
7  PubMed abstract 6095185
8  PubMed abstract 6087806
9  PubMed abstract 7447938
10  PubMed abstract 475783
Domain NameACTH_domain  NPP  Op_neuropeptide  
Hormone NameMelanotropin alpha (Alpha-MSH)
Mature Hormone SequenceSYSMEHFRWGKPIGH
Position of mature hormone in Pre-Hormone protein15 Residues from position (98-112)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated