A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 10697 |
| Swiss-prot Accession number | P37085 (Sequence in FASTA format) |
| Description | Pigment-dispersing hormone A precursor [Contains: PDH precursor-related peptide (PRPP); Pigment-dispersing hormone A (PDH A) (Light-adapting distal retinal pigment hormone A) (DRPH A)]. |
| Source organism | Orconectes limosus (Spinycheek crayfish) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Astacoidea; Cambaridae; Orconectes; Faxonius. |
| Subcellular location | Secreted protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the arthropod PDH family. |
| Tissue Specificity | Optical ganglia of the eyestalk |
| Post translational modification | N/A |
| Function | Causes the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas. May also function as a neurotransmitter and/or neuromodulator |
| Protein Length | 76 Amino acids |
| Molecular weight | 8281 |
| References | 1 PubMed abstract 8477858 |
| Domain Name | Pigment_DH |
| Hormone Name | Pigment-dispersing hormone A |
| Mature Hormone Sequence | GPHKRNSELINSILGLPKVMNEA |
| Position of mature hormone in Pre-Hormone protein | 18 Residues from position (56-73) |
| Receptor | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |