A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10335
Swiss-prot Accession numberQ8HYE5 (Sequence in FASTA format)
DescriptionSomatotropin precursor (Growth hormone).
Source organismAiluropoda melanoleuca (Giant panda)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae;Ailuropoda.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the somatotropin/prolactin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues
Protein Length216 Amino acids
Molecular weight24383
References1  PubMed abstract 12781978
Domain NameHormone_1  
Hormone NameSomatotropin
Mature Hormone SequenceFPAMPLSSLFANAVLRAQHLHQLAADTYKEFERAYIPEGQRYSIQNAQAAFCFSETIPAPTGKDEAQQRSDVELLRFSLLLIQSWLGPVQFLSRVFTNSLVFGTSDRVYEKLKDLEEGIQALMRELEDGSPRAGQILKPTYDKFDTSLRSDDALLKNYGLLSCFKKDLHKAETYLRVMKCRRFVESSCAF
Position of mature hormone in Pre-Hormone protein190 Residues from position (27-216)
ReceptorQ95JF2    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
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