A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10091
Swiss-prot Accession numberQ25589 (Sequence in FASTA format)
DescriptionCrustacean hyperglycemic hormones A precursor (CHH A) [Contains: CHHprecursor-related peptide A (CPRP A); Crustacean hyperglycemic hormone(CHH)].
Source organismOrconectes limosus (Spinycheek crayfish)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Astacoidea; Cambaridae; Orconectes; Faxonius.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
Tissue SpecificityProduced by the medulla terminalis X-organ in the eyestalks and transported to the sinus gland where they are stored and released
Post translational modificationN/A
FunctionHormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction
Protein Length135 Amino acids
Molecular weight15086
References1  PubMed abstract 7925379
2  PubMed abstract 1788131
3  PubMed abstract 1800954
Domain NameCrust_neurohorm  
Hormone NameCrustacean hyperglycemic hormone
Mature Hormone SequenceQVFDQACKGIYDRAIFKKLDRVCEDCYNLYRKPYVATTCRQNCYANSVFRQCLDDLLLIDVLDEYISGVQTV
Position of mature hormone in Pre-Hormone protein72 Residues from position (62-133)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated