A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10014
Swiss-prot Accession numberP06298 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin A precursor (Pro-opiomelanocortin A) (POMC-A)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismXenopus laevis (African clawed frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length259 Amino acids
Molecular weight29879
References1  PubMed abstract 3754961
2  PubMed abstract 1584015
3   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
4  PubMed abstract 3840481
5  PubMed abstract 2564347
6  PubMed abstract 3754961
7  PubMed abstract 1584015
8   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
9  PubMed abstract 3840481
10  PubMed abstract 2564347
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameMelanotropin beta (Beta-MSH)
Mature Hormone SequenceNGNYRMHHFRWGSPPKD
Position of mature hormone in Pre-Hormone protein17 Residues from position (210-226)
ReceptorN/A
Gene ID380532      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated