A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 10333 |
| Swiss-prot Accession number | Q8CHK2 (Sequence in FASTA format) |
| Description | Relaxin-3 precursor (Prorelaxin M3) (Insulin-like peptide INSL7)(Insulin-like peptide 7) [Contains: Relaxin-3 B chain; Relaxin-3 Achain]. |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the insulin family. |
| Tissue Specificity | High expression in the brain localized to the pons/medulla with highest levels in pars ventromedialis of the dorsal tegmental nucleus. Significant expression is also detected in the spleen, thymus, lung, testis and ovary |
| Post translational modification | N/A |
| Function | May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 and relaxin-3 receptor-2 |
| Protein Length | 141 Amino acids |
| Molecular weight | 14926 |
| References | 1 PubMed abstract 12686464 2 PubMed abstract 11689565 |
| Domain Name | Insulin |
| Hormone Name | Relaxin-3 A chain |
| Mature Hormone Sequence | DVLAGLSSSCCEWGCSKSQISSLC |
| Position of mature hormone in Pre-Hormone protein | 24 Residues from position (118-141) |
| Receptor | Q8BGE9 Detail in HMRbase Q7TQP4 Detail in HMRbase Q91ZZ5 Detail in HMRbase |
| Gene ID | 212108 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |