A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10336
Swiss-prot Accession numberQ8R1I2 (Sequence in FASTA format)
DescriptionGastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear
Protein Length146 Amino acids
Molecular weight15659
References1  PubMed abstract 16141072
2  PubMed abstract 15489334
Domain NameBombesin  
Hormone NameGastrin-releasing peptide
Mature Hormone SequenceAPVSTGAGGGTVLAKMYPRGSHWAVGHLM
Position of mature hormone in Pre-Hormone protein29 Residues from position (24-52)
ReceptorP21729    Detail in HMRbase   
Gene ID225642      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 2

HMRbase accession number10337
Swiss-prot Accession numberQ8R1I2 (Sequence in FASTA format)
DescriptionGastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionN/A
Protein Length146 Amino acids
Molecular weight15659
References1  PubMed abstract 16141072
2  PubMed abstract 15489334
Domain NameBombesin  
Hormone NameNeuromedin-C
Mature Hormone SequenceGSHWAVGHLM
Position of mature hormone in Pre-Hormone protein10 Residues from position (43-52)
ReceptorP21729    Detail in HMRbase   
Gene ID225642      
PDB IDN/A
Drugpediawiki
Comments