A database of hormones and their receptors |
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HMRbase accession number | 11466 |
Swiss-prot Accession number | P49000 (Sequence in FASTA format) |
Description | Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone)(AMH) (Muellerian-inhibiting substance). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Secreted protein (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the TGF-beta family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin |
Protein Length | 553 Amino acids |
Molecular weight | 58889 |
References | 1 PubMed abstract 1572639 |
Domain Name | N/A |
Hormone Name | Muellerian-inhibiting factor |
Mature Hormone Sequence | N/A |
Position of mature hormone in Pre-Hormone protein | N/A Residues from position |
Receptor | Q62893
Detail in HMRbase |
Gene ID | 25378 |
PDB ID | N/A |
Drugpedia | wiki |
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