A database of hormones and their receptors
Non-peptide Hormone

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HMRbase accession number1081
PubChem ID5754
Hormone nameHydrocortisone
DescriptionThe main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.
SynonymsHydrocortisone Cortisol Cortef Acticort Cetacort Hytone Dihydrocostisone Hydrocortisyl Hydrocortone Corticreme
Molecular weight362.46
Molecular formulaC21H30O5
IUPAC Name(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Canonical smilesCC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O
Isomeric smilesC[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O
Structure
   
PDB file
SDF file
MOL file
PDB ID2Q1V  2V95  2VDY  
KEGG IDC00735  D00088  
HMDB IDHMDB00063
Melting Point220(EXP)
Log P1.61(EXP)
Water Solubility320(EXP) at 25C
DrugBank IDDB00741
Drugpediawiki
ReceptorP04150   Detail in HMRbase   
Comments
ReferencesPubchem,HMDB