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4168 details
Primary information
Hemolytik ID4168
PMID15127790
YEAR2004
SEQUENCEAKKVFKRLGIGAVLKVLTTG
LENGTH20
NAMEHP(2-9)-ME(1-12)
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY0% hemolysis upto 100µM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCHHHHTTTCCTTSCCCCSCC
SMILESN[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEDesign of novel analogues with potent antibiotic activity based on the antimicrobial peptide, HP(2-9)-ME(1-12).
AUTHORSPark Y,Kim HN,Park SN,Jang SH,Choi CH,Lim HT
JOURNALBiotechnol Lett. 2004 Mar;26(6):493-8.