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4110 details
Primary information
Hemolytik ID4110
PMID15513914
YEAR2004
SEQUENCEFLPLIGRVLSGIL
LENGTH13
NAMETemporin A
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntiparasitic
ACTIVITYLC50 >120μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCHHHHTSCCC
SMILESN[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA P56917 NA NA NA NA NA
Reference Informaiton
ARTICLETemporins, small antimicrobial peptides with leishmanicidal activity.
AUTHORSMangoni ML,Saugar JM,Dellisanti M,Barra D,Simmaco M
JOURNALJ Biol Chem. 2005 Jan 14;280(2):984-90. Epub 2004 Oct 28.