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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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4098 details
Primary information
Hemolytik ID4098
PMID11937508
YEAR2002
SEQUENCEALWKTLLKKVLKA
LENGTH13
NAMEK4-S4(1-13)NH2
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntiparasitic
ACTIVITY3% hemolysis at 10μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCTHHHHGGGSCCC
SMILESN[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
2dd6A NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEDirect interaction of dermaseptin S4 aminoheptanoyl derivative with intraerythrocytic malaria parasite leading to increased specific antiparasitic activity in culture.
AUTHORSEfron L,Dagan A,Gaidukov L,Ginsburg H
JOURNALJ Biol Chem. 2002 Jul 5;277(27):24067-72. Epub 2002 Apr 5.