Primary information |
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Hemolytik ID | 4077 |
PMID | 15885852 |
YEAR | 2005 |
SEQUENCE | GFMKYIKPLIPHAVKAIKKLI |
LENGTH | 21 |
NAME | Kassinatuerin-1 (Lys7, Lys18, Lys19) |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | LD50 =40μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCCCCCCCCCHHHHHHHHTTC |
SMILES | NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Antimicrobial and cytolytic properties of the frog skin peptide, kassinatuerin-1 and its L- and D-lysine-substituted derivatives. |
AUTHORS | Conlon JM,Abraham B,Galadari S,Knoop FC,Sonnevend A |
JOURNAL | Peptides. 2005 Nov;26(11):2104-10. |