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4065 details
Primary information
Hemolytik ID4065
PMID15328050
YEAR2004
SEQUENCEFWGALAKGALKLIPSLFSSFSKKD
LENGTH24
NAMEPin2
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY85% hemolysis at 12.5μM
RBCs SOURCEGuinea-pig
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCTTSCCSGGGSHHHHHHHHTTCC
SMILESN[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA P83240 NA NA NA NA NA
Reference Informaiton
ARTICLEPore formation of phospholipid membranes by the action of two hemolytic arachnid peptides of different size.
AUTHORSBelokoneva OS,Satake H,Mal'tseva EL,Pal'mina NP,Villegas E,Nakajima T
JOURNALBiochim Biophys Acta. 2004 Aug 30;1664(2):182-8.