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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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4058 details
Primary information
Hemolytik ID4058
PMID12804591
YEAR2003
SEQUENCEFLPILGKLLSGIL
LENGTH10
NAMEMRP
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITYLC50 = 8μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCTHHHHSCCC
SMILESN[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEA melittin-related peptide from the skin of the Japanese frog, Rana tagoi, with antimicrobial and cytolytic properties.
AUTHORSConlon JM,Sonnevend A,Patel M,Camasamudram V,Nowotny N,Zilahi E,Iwamuro S, Nielsen, Per ,Nielsen PF
JOURNALBiochem Biophys Res Commun. 2003 Jun 27;306(2):496-500.