Primary information |
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Hemolytik ID | 4058 |
PMID | 12804591 |
YEAR | 2003 |
SEQUENCE | FLPILGKLLSGIL |
LENGTH | 10 |
NAME | MRP |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | LC50 = 8μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCCCTHHHHSCCC |
SMILES | N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | A melittin-related peptide from the skin of the Japanese frog, Rana tagoi, with antimicrobial and cytolytic properties. |
AUTHORS | Conlon JM,Sonnevend A,Patel M,Camasamudram V,Nowotny N,Zilahi E,Iwamuro S, Nielsen, Per ,Nielsen PF |
JOURNAL | Biochem Biophys Res Commun. 2003 Jun 27;306(2):496-500. |