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3996 details
Primary information
Hemolytik ID3996
PMID16488428
YEAR2006
SEQUENCESAISCGETCFKFKCYTPRCSCSYPVCK
LENGTH27
NAMEViolacin A
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicCyclic
StereochemistryL
Modified ResiduesNone
FUNCTIONUterotonic and Insecticidal and Anti-HIV and Antimicrobial and Anti-neurotensive and Cytotoxic and Hemolytic
ACTIVITY30% hemolysis at 1.5μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCSCCCSTTCCCTTCCSCCSCSCCCCC
SMILESN[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
2fqaA NA NA Q2HY54
from
80
TO
106		 NA NA NA NA
Reference Informaiton
ARTICLEDiscovery and characterization of a linear cyclotide from Viola odorata: implications for the processing of circular proteins.
AUTHORSIreland DC,Colgrave ML,Nguyencong P,Daly NL
JOURNALJ Mol Biol. 2006 Apr 14;357(5):1522-35. Epub 2006 Feb 2.