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3985 details
Primary information
Hemolytik ID3985
PMID18855761
YEAR2008
SEQUENCEKWKLFKKIpKFLHLAKKF
LENGTH18
NAMEP18-D-Pro
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryMix (Contains both L and D amino acids)
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITYMHC <200μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCSCSCCHHHHTCSSCC
SMILESN[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEAntimicrobial and anti-inflammatory activities of designed antimicrobial peptide P18 analogues.
AUTHORSNan YH
JOURNALProtein Pept Lett. 2008;15(8):861-5.