| Primary information |
|---|
| Hemolytik ID | 3808 |
| PMID | 9518597 |
| YEAR | 1998 |
| SEQUENCE | Aib-P-Aib-A-Aib-AQ-Aib-V-Aib-GL-Aib-PV-Aib-Aib-EQ |
| LENGTH | 19 |
| NAME | Alam-P14 |
| C-ter Modification | Pheol |
| N-ter Modification | Acetylation |
| Linear/Cyclic | Linear |
| Stereochemistry | L |
| Modified Residues | Aib = α- methylalanine |
| FUNCTION | Cytolytic |
| ACTIVITY | EC50 =30μM |
| RBCs SOURCE | Human |
| Secondary information |
|---|
| Properties | Physico-Chemical details |
| STRUCTURE | |
| DSSP states | NA |
| SMILES | NA |
| External Links |
|---|
| PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
| NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
|
| Reference Informaiton |
|---|
| ARTICLE | Proline at position 14 of alamethicin is essential for hemolytic activity, catecholamine secretion from chromaffin cells and enhanced metabolic activity in endothelial cells. |
| AUTHORS | Dathe M,Kaduk C,Tachikawa E, Melzig, M ,Melzig MF,Wenschuh H |
| JOURNAL | Biochim Biophys Acta. 1998 Mar 6;1370(1):175-83. |
