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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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3772 details
Primary information
Hemolytik ID3772
PMID14636071
YEAR2003
SEQUENCELVRGCWTKSYPPKPCFVR
LENGTH18
NAMEpLR
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicCyclic
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY85% hemolysis at 100μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCTTSSCSSSSSSSCSCCC
SMILESN[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLERanacyclins, a new family of short cyclic antimicrobial peptides: biological function, mode of action, and parameters involved in target specificity.
AUTHORSMangoni ML,Papo N,Mignogna G,Andreu D,Shai Y,Barra D
JOURNALBiochemistry. 2003 Dec 2;42(47):14023-35.