Primary information |
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Hemolytik ID | 3771 |
PMID | 14636071 |
YEAR | 2003 |
SEQUENCE | SAPRGCWTKSYPPKPCK |
LENGTH | 17 |
NAME | Ranacyclin E |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Cyclic |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | 55% hemolysis at 100μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCSCCSCCCCCCSSCCC |
SMILES | N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
NA |
NA |
P83663 |
NA |
NA |
NA |
NA |
NA |
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Reference Informaiton |
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ARTICLE | Ranacyclins, a new family of short cyclic antimicrobial peptides: biological function, mode of action, and parameters involved in target specificity. |
AUTHORS | Mangoni ML,Papo N,Mignogna G,Andreu D,Shai Y,Barra D |
JOURNAL | Biochemistry. 2003 Dec 2;42(47):14023-35. |