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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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3766 details
Primary information
Hemolytik ID3766
PMID10606532
YEAR1999
SEQUENCEKKllKLKlKwKK
LENGTH12
NAME[D]L3,4,8-K7L4Wc
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryMix (Contains both L and D amino acids)
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY0% hemolysis at 50μM (Non hemolytic)
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCTTCCCCCCC
SMILESN[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEStructure and organization of hemolytic and nonhemolytic diastereomers of antimicrobial peptides in membranes.
AUTHORSHong J,Oren Z
JOURNALBiochemistry. 1999 Dec 21;38(51):16963-73.