Primary information |
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Hemolytik ID | 3758 |
PMID | 10606532 |
YEAR | 1999 |
SEQUENCE | KWllLLKlLlLK |
LENGTH | 12 |
NAME | [D]L3,4,8,10-K3L8Wn |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | Mix (Contains both L and D amino acids) |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | 31% hemolysis at 50μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CHHHHHHHHTCC |
SMILES | N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Structure and organization of hemolytic and nonhemolytic diastereomers of antimicrobial peptides in membranes. |
AUTHORS | Hong J,Oren Z |
JOURNAL | Biochemistry. 1999 Dec 21;38(51):16963-73. |