Primary information |
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Hemolytik ID | 3714 |
PMID | 23415652 |
YEAR | 2013 |
SEQUENCE | LLGMIPLAISAISALSKL |
LENGTH | 18 |
NAME | Medusin-AC |
C-ter Modification | Free |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | 8.7% hemolysis at 32mg/ml |
RBCs SOURCE | Horse |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCSSCHHHHHHHHHHTTC |
SMILES | N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Medusins: a new class of antimicrobial peptides from the skin secretions of phyllomedusine frogs. |
AUTHORS | Xi X,Li R,Jiang Y,Lin Y,Wu Y,Zhou M,Xu J,Wang L,Chen T |
JOURNAL | Biochimie. 2013 Jun;95(6):1288-96. doi: 10.1016/j.biochi.2013.02.005. Epub 2013 Feb 14. |