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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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3655 details
Primary information
Hemolytik ID3655
PMID8849687
YEAR1996
SEQUENCEILPWKWPWWPWRR
LENGTH13
NAMEIndolicidin
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY~20% hemolysis at 10µM
RBCs SOURCERat
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCCCSSCSSCC
SMILESN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
1g89A NA NA NA NA NA NA NA
Reference Informaiton
ARTICLERequirements for antibacterial and hemolytic activities in the bovine neutrophil derived 13-residue peptide indolicidin.
AUTHORSSubbalakshmi C,Krishnakumari V,Nagaraj R
JOURNALFEBS Lett. 1996 Oct 14;395(1):48-52.