Primary information |
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Hemolytik ID | 3618 |
PMID | 19088182 |
YEAR | 2009 |
SEQUENCE | FFGHLFKLATKIIPSLFQ |
LENGTH | 18 |
NAME | Meucin-18 |
C-ter Modification | Free |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | >95% hemolysis at 25µM |
RBCs SOURCE | Rabbit |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CTTHHHHHGGGGSSSSCC |
SMILES | N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Structural and functional characterization of two genetically related meucin peptides highlights evolutionary divergence and convergence in antimicrobial peptides. |
AUTHORS | Gao B,Sherman P,Luo L,Bowie J |
JOURNAL | FASEB J. 2009 Apr;23(4):1230-45. doi: 10.1096/fj.08-122317. Epub 2008 Dec 16. |