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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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3522 details
Primary information
Hemolytik ID3522
PMID9166783
YEAR1997
SEQUENCEGIGKFLHSAKKFGKAFVGEIMNS
LENGTH23
NAMEM2a
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntibacterial
ACTIVITY30% hemolysis at 150μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCSHHHHHHTTTCSSGGGGTTTC
SMILESNCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
2magA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEPeptide hydrophobicity controls the activity and selectivity of magainin 2 amide in interaction with membranes.
AUTHORSWieprecht T,Dathe M,Beyermann M,Krause E,Maloy WL,MacDonald DL
JOURNALBiochemistry. 1997 May 20;36(20):6124-32.