Primary information |
---|
Hemolytik ID | 3300 |
PMID | 8027544 |
YEAR | 1994 |
SEQUENCE | QQRKRKGIGAVLKVLTTGLPALISWI |
LENGTH | 26 |
NAME | Melttin-(26-21) (1-20) |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Cytolytic |
ACTIVITY | 15% hemolysis at 120μM compared with melittin |
RBCs SOURCE | Mouse |
Secondary information |
---|
Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCSSCSCSHHHHHHHHHHSCTTTTCC |
SMILES | N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)O |
External Links |
---|
PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
|
Reference Informaiton |
---|
ARTICLE | Structure-immunogenicity relationship of melittin, its transposed analogues, and D-melittin. |
AUTHORS | King TP,Wade D,Coscia MR,Mitchell S,Kochoumian L |
JOURNAL | J Immunol. 1994 Aug 1;153(3):1124-31. |