Primary information |
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Hemolytik ID | 3256 |
PMID | 23403131 |
YEAR | 2013 |
SEQUENCE | GILNTIKSIASKLKRKAK |
LENGTH | 18 |
NAME | K4N Δ(K12-Q18; Ν26−Α29) |
C-ter Modification | Free |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | EC50 =139μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCCCHHHHHHHHHGGGCC |
SMILES | NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Enhanced antimicrobial activity of novel synthetic peptides derived from vejovine and hadrurin. |
AUTHORS | Sanchez-Vasquez L,Silva-Sanchez J,Jimenez-Vargas JM,Rodriguez-Romero A,Munoz-Garay C,Rodriguez MC,Gurrola GB |
JOURNAL | Biochim Biophys Acta. 2013 Jun;1830(6):3427-36. doi: 10.1016/j.bbagen.2013.01.028. Epub 2013 Feb 9. |