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3246 details
Primary information
Hemolytik ID3246
PMID23262358
YEAR2013
SEQUENCEDLLGTLGNLPLPFI
LENGTH14
NAMEfrenatin 2D
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONImmunomodulatory
ACTIVITYNo hemolysis upto 500μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCSSSTTSCCCSCC
SMILESN[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEAn immunomodulatory peptide related to frenatin 2 from skin secretions of the Tyrrhenian painted frog Discoglossus sardus (Alytidae).
AUTHORSConlon JM,Mechkarska M,Pantic JM,Lukic ML,Coquet L,Leprince J, Nielsen, Per ,Nielsen PF
JOURNALPeptides. 2013 Feb;40:65-71. doi: 10.1016/j.peptides.2012.12.012. Epub 2012 Dec 20.