Primary information |
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Hemolytik ID | 3246 |
PMID | 23262358 |
YEAR | 2013 |
SEQUENCE | DLLGTLGNLPLPFI |
LENGTH | 14 |
NAME | frenatin 2D |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Immunomodulatory |
ACTIVITY | No hemolysis upto 500μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCSSSTTSCCCSCC |
SMILES | N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | An immunomodulatory peptide related to frenatin 2 from skin secretions of the Tyrrhenian painted frog Discoglossus sardus (Alytidae). |
AUTHORS | Conlon JM,Mechkarska M,Pantic JM,Lukic ML,Coquet L,Leprince J, Nielsen, Per ,Nielsen PF |
JOURNAL | Peptides. 2013 Feb;40:65-71. doi: 10.1016/j.peptides.2012.12.012. Epub 2012 Dec 20. |