Home Page
   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

Detailed description page of Hemolytik

This page displays user query in tabular form.

3212 details
Primary information
Hemolytik ID3212
PMID22974815
YEAR2013
SEQUENCEFVPWFSKFlGRIL
LENGTH13
NAME[Pro3, DLeu9]TL
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryMix (Contains both L and D amino acids)
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY9% hemolysis at 48μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCTTTSSSSCCC
SMILESN[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLEThe effect of d-amino acid substitution on the selectivity of temporin L towards target cells: identification of a potent anti-Candida peptide.
AUTHORSGrieco P,Carotenuto A,Auriemma L,Saviello MR,Campiglia P,Gomez-Monterrey IM,Marcellini L,Luca V,Barra D,Novellino E
JOURNALBiochim Biophys Acta. 2013 Feb;1828(2):652-60. doi: 10.1016/j.bbamem.2012.08.027. Epub 2012 Sep 10.