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   HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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3189 details
Primary information
Hemolytik ID3189
PMID22974815
YEAR2013
SEQUENCEFVQWFSKFLGRIL
LENGTH13
NAMETL
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY94% hemolysis at 24μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCHHHHHHHHHCCC
SMILESN[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA P57104 NA NA NA NA NA
Reference Informaiton
ARTICLEThe effect of d-amino acid substitution on the selectivity of temporin L towards target cells: identification of a potent anti-Candida peptide.
AUTHORSGrieco P,Carotenuto A,Auriemma L,Saviello MR,Campiglia P,Gomez-Monterrey IM,Marcellini L,Luca V,Barra D,Novellino E
JOURNALBiochim Biophys Acta. 2013 Feb;1828(2):652-60. doi: 10.1016/j.bbamem.2012.08.027. Epub 2012 Sep 10.