Primary information |
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Hemolytik ID | 3179 |
PMID | 22965637 |
YEAR | 2013 |
SEQUENCE | ILGKLLSTAAKLLSKL |
LENGTH | 16 |
NAME | G11K,N15K |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | CPP |
ACTIVITY | LC50 =16μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CGGGGGHHHHHHHTTC |
SMILES | N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Transformation of the naturally occurring frog skin peptide, alyteserin-2a into a potent, non-toxic anti-cancer agent. |
AUTHORS | Conlon JM,Mechkarska M,Prajeep M,Arafat K,Zaric M,Lukic ML |
JOURNAL | Amino Acids. 2013 Feb;44(2):715-23. doi: 10.1007/s00726-012-1395-7. Epub 2012 Sep 11. |