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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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3169 details
Primary information
Hemolytik ID3169
PMID22965637
YEAR2013
SEQUENCEILKKLLSTAAGLLSNL
LENGTH16
NAMEG3K
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONCPP
ACTIVITYLC50 =105μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCHHHHHHHHHTTCCCC
SMILESN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLETransformation of the naturally occurring frog skin peptide, alyteserin-2a into a potent, non-toxic anti-cancer agent.
AUTHORSConlon JM,Mechkarska M,Prajeep M,Arafat K,Zaric M,Lukic ML
JOURNALAmino Acids. 2013 Feb;44(2):715-23. doi: 10.1007/s00726-012-1395-7. Epub 2012 Sep 11.