Primary information |
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Hemolytik ID | 3153 |
PMID | 22800690 |
YEAR | 2012 |
SEQUENCE | GMATAAGTTLGKLAKFVIGAV |
LENGTH | 21 |
NAME | PGLa-SE2 |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | LC50 >160μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCCCCCCSHHHHHHHHHCCCC |
SMILES | NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Host-defense peptides in skin secretions of the tetraploid frog Silurana epitropicalis with potent activity against methicillin-resistant Staphylococcus aureus (MRSA). |
AUTHORS | Conlon JM,Mechkarska M,Prajeep M,Sonnevend A,Coquet L,Leprince J,Jouenne T,Vaudry H |
JOURNAL | Peptides. 2012 Sep;37(1):113-9. doi: 10.1016/j.peptides.2012.07.005. Epub 2012 Jul 16. |