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  HEMOLYTIK: A Database of Hemolytic and Non-hemolytic Peptides

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3139 details
Primary information
Hemolytik ID3139
PMID21682682
YEAR2011
SEQUENCELGRVDIHVWDGVYIRGR
LENGTH17
NAMEKK42-63-3H
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONCytotoxic
ACTIVITY5.9% hemolysis at 100μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCCCCCSSSSSSCTTCC
SMILESN[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
2p5jA NA NA NA NA NA NA NA
Reference Informaiton
ARTICLETherapeutic potential of peptides with neutralizing ability towards the venom and toxin (CaTx-I) of crotalus adamanteus.
AUTHORSSamy RP,Thwin MM,Stiles BG,Bow H,Chow VT
JOURNALCurr Top Med Chem. 2011;11(20):2540-55.