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3121 details
Primary information
Hemolytik ID3121
PMID21241661
YEAR2011
SEQUENCECVYAYVRVRGVLVRYRRCW
LENGTH19
NAMEArenicin-1(analog-1)
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITY0% hemolysis at 50μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCCSTTSCCCCCCCCCCSCC
SMILESN[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NA 2jsbA
from
3
TO
21		 NA Q5SC60
from
184
TO
202		 NA NA NA NA
Reference Informaiton
ARTICLEThe characteristic region of arenicin-1 involved with a bacterial membrane targeting mechanism.
AUTHORSCho J
JOURNALBiochem Biophys Res Commun. 2011 Feb 18;405(3):422-7. doi: 10.1016/j.bbrc.2011.01.046. Epub 2011 Jan 15.