Primary information |
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Hemolytik ID | 3119 |
PMID | 21241661 |
YEAR | 2011 |
SEQUENCE | RWCVYAYVRVRGVLVRYRRCW |
LENGTH | 21 |
NAME | Arenicin-1 |
C-ter Modification | Free |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | 35% hemolysis at 50μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCSCCTTSCCCCCSCCCCCCC |
SMILES | N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1c[nH]c(C)c1CC)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
2jsbA |
NA |
NA |
Q5SC60 from 182 TO 202 |
NA |
NA |
NA |
NA |
|
Reference Informaiton |
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ARTICLE | The characteristic region of arenicin-1 involved with a bacterial membrane targeting mechanism. |
AUTHORS | Cho J |
JOURNAL | Biochem Biophys Res Commun. 2011 Feb 18;405(3):422-7. doi: 10.1016/j.bbrc.2011.01.046. Epub 2011 Jan 15. |