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3084 details
Primary information
Hemolytik ID3084
PMID20603168
YEAR2010
SEQUENCEGLKEIFKAGLGSLVKGIAAHVAS
LENGTH23
NAMEN-Pal,E4K
C-ter ModificationFree
N-ter Modificationpalmitate(pal)
Linear/CyclicLinear
StereochemistryL
Modified ResiduesNone
FUNCTIONAntimicrobial
ACTIVITYLC50 =10μM
RBCs SOURCEHuman
Secondary information
PropertiesPhysico-Chemical details
STRUCTURE
Natural StructureFinal Structure
DSSP statesCTHHHHTSSSTTHHHHHHHHHTC
SMILESNCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)O
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
2l5rA NA NA NA H0USY4 NA NA NA
Reference Informaiton
ARTICLEPotent and rapid bactericidal action of alyteserin-1c and its [E4K] analog against multidrug-resistant strains of Acinetobacter baumannii.
AUTHORSConlon JM,Ahmed E,Pal T
JOURNALPeptides. 2010 Oct;31(10):1806-10. doi: 10.1016/j.peptides.2010.06.032. Epub 2010 Jul 11.