Primary information |
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Hemolytik ID | 3063 |
PMID | 20399752 |
YEAR | 2010 |
SEQUENCE | KRAKKFFKKPK |
LENGTH | 11 |
NAME | ATRA-2 |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
Stereochemistry | L |
Modified Residues | None |
FUNCTION | Antimicrobial |
ACTIVITY | EC50 =107μM |
RBCs SOURCE | Human |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CGGGTSSSTTC |
SMILES | N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
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Reference Informaiton |
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ARTICLE | Antimicrobial and antibiofilm activity of cathelicidins and short, synthetic peptides against Francisella. |
AUTHORS | Amer LS,Bishop BM |
JOURNAL | Biochem Biophys Res Commun. 2010 May 28;396(2):246-51. doi: 10.1016/j.bbrc.2010.04.073. Epub 2010 Apr 23. |